Kaleo, the makers of Evzio, have recently discontinued the production of the Evzio naloxone auto-injector and its generic equivalent. The FDA Orange Book now lists the brand and generic products with “discontinued” marketing statuses. The FDA approved Evzio auto-injector to temporarily reverse the effects of an opioid overdose. The drug is designed to be administered outside of the healthcare setting by family members or caregivers.
Alternative naloxone products such as Narcan nasal spray continue to be available for use in an overdose situation. In the workers' compensation or auto casualty industry, patients may have been prescribed the naloxone auto-injector along with an opioid prescription. The reason for discontinuation of the auto-injectors is unknown; however, the existing product will remain in pharmacies and Kaleo did not express concerns regarding continued use of the product through the expiration date. Mitchell Pharmacy Solutions will continue to monitor the situation and provide updates where relevant.
If you have any additional questions about this alert, please contact your client services manager.